![]() ![]() ![]() You may be at a higher risk of developing shingles (herpes zoster) while using OPZELURA. You should not start using OPZELURA if you have any kind of infection unless your healthcare provider tells you it is okay. OPZELURA should not be used in people with an active, serious infection, including localized infections. Your healthcare provider should watch you closely for signs and symptoms of TB during treatment with OPZELURA. Some people have had serious infections of their lungs while taking OPZELURA. Some people have been hospitalized or died from these infections. Some people have had serious infections while taking JAK inhibitors by mouth, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses that can spread throughout the body. JAK inhibitors can lower the ability of your immune system to fight infections. JAK inhibitors are medicines that affect your immune system. Ruxolitinib belongs to a class of medicines called Janus kinase (JAK) inhibitors. Serious Infections: OPZELURA contains ruxolitinib. OPZELURA may cause serious side effects, including: Do not use OPZELURA in your eyes, mouth, or vagina. Incyte reserves the right to rescind, revoke, or amend this offer at any time without notice.įor questions or additional support call 833-613-2333 or email Incyte may also de-identify the patient’s information and use the de-identified information for Incyte’s business purposes Incyte may also share the patient’s information with its subsidiaries, affiliates, representatives, agents, and contractors.
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![]() ![]() His memories include, “… people jammed the banks of Lake Amador to sunbathe, drink wine, smoke marijuana and listen to an all-star roster of musicians at the Gold Rush Rock Music Festival. James Hackworth was 22 years old when he and his wife and two kids attended the Gold Rush Festival. Unfortunately, there is no video or recording of the event. It is a wonderful story by someone who humbly tells the story with lots of detail. That video can be found on YouTube in four parts. ![]() He recently assisted in a video report of the event. He describes the event as a perfect combination of location, music, stage, PA, and weather. Strand was the manager of Country Weather, one of the bands that appeared. He and his family were the financial backers. Robert Strand promoted the event and 40,000 people showed up. One must imagine the impact Tina would have had on 400,000 people that day, on the album that she surely would have been on, and the movie she absolutely appeared in. There certainly were black performers and there were bands playing blues and blues/rock, but there was no Taj Mahal. If there is a criticism of Woodstock’s three-day lineup, it is that given the year and perspective, there were no black bands as such. This could be a very nice day in the country. There wasn’t anything like Ike and Tina Turner at Woodstock. You knew about Santana before Woodstock and knew they were pretty good. Not bad at all:ġ969 Gold Rush Festival Day in the Country You hear about a one-day festival coming up in Lake Amador, which is about 50 miles southeast of Sacramento. It’s October 1969 and you’ve heard all about that Woodstock Music and Art Fair back east, but you were on the west coast. 1969 Gold Rush Festival Country Weather – “Over and Over” OctoAmador, CA 1969 festival #44 ![]() ![]() It's easy to put books on the device, much easier than using a Kindle. With more storage, a faster E Ink screen, and Bluetooth® wireless technology so you can listen to Kobo Audiobooks, Kobo Libra 2 is an integral part of your rich reading life. This allows plenty of comfortable reading positions without the risk of hand cramps (from the aforementioned thinness and lack of thick shoulder). 14.99 Add To Cart Your eReader, your story The next-generation Kobo Libra 2 is the embodiment of your reading style. No sources that perform objective hands-on testing have deemed the Kobo Libra 2 worthy of being included in their E. Depending on how much you're willing to spend, either of these options will serve you well. With the folding case, which I highly recommend you buy, it's a bit thicker, but it stands by itself. I dont have a Clara HD, so can only answer some of your questions. The Kobo Libra 2 and Kobo Clara HD make for very strong choices and are great E-readers for their respective 179 and 109 asking prices. Without the folding case (sold separately) it's thin and super light. Kobo driver: support the new Kobo Clara 2e When running calibre with the. Looking like a natural page is not as important as being easy to read, which the Clara 2E more than handles. Cover download: Allowing saving alternate covers to disk or in the books data. However, having the recessed screen means I make fewer accidental touches. It looks ever so slightly more naturally like a page and having the screen flush with the bezel is more aesthetically pleasing. ![]() The Libra 2's girth makes it slightly more difficult to fit into a bag while the Clara 2E can easily find a space in an overpacked carry-on bag.ĭoing a direct comparison with the Kindle Paperwhite, it's hard to deny that the Paperwhite screen looks a tiny bit better. However, not having that larger shoulder and buttons means the Clara 2E is much thinner and bag-friendly. ![]() I find that a bit more comfortable to hold for long periods and I prefer the buttons for navigation when it's cold. It makes for a smoother and more enjoyable reading experience. One thing I love about the Kobo Libra 2 is its thicker right side which also accommodates 2 buttons for page turning. Why is Kobo Libra 2 better than Kobo Clara 2E 16.67 bigger screen size 7' vs 6' 16GB more internal storage 32GB vs 16GB 36. The Clara HD feels much faster with the screen responding immediately to my input. This sharp Full HD screen lets you read more comfortably than the HD screen of the Kobo Clara. ![]() It's also got a smaller (but not too small) 6-inch screen compared to the 6.8-inch Paperwhite and 7-inch Libra 2. The 6.8-inch screen of the Kobo Libra H2O is slightly larger than that of the Clara HD. The Clara 2E is the ereader for people who never want to be without a good book but also don't want books taking up too much room in their handbag.Īt 171 grams, it suits the weight requirement, coming in at 44 grams lighter than the Kobo Libra 2 and 34 grams lighter than the Kindle Paperwhite. ![]() ![]() When reviewing the LG gram 17, we were particularly impressed with how light it was. So whether you’re running AutoCAD or any other 3D modelling software, you can be sure of a smooth, responsive and speedy experience. It’s a strong performer overall, too, with the 11th Generation Intel Core processor, working with well the 8-16GB RAM and Intel’s integrated Iris Xe graphics. Plus with a resolution of 2,560 x 1600, you get the high level of detail you need when working with sophisticated 3D models. This WQXGA IPS display is both big and beautiful, with vivid and nuanced colours and deep, rich blacks. But maybe you want to see your CAD designs on a bigger display, allowing you to focus better on all the small details? In which case, let us point you towards the LG Gram 17, with its 17-inch screen. The laptops we’ve featured so far have all had mid-sized screens. See our MacBook Pro 14-inch review for more details. But if you’re looking for a premium Apple laptop and are willing to pay the price, you won’t find better. ![]() This laptop is very much the Rolls Royce option of MacBooks, and may be overkill for a lot of people’s needs. You’ll also benefit from the most beautiful, super-high res screen, and up to a whopping 8TB of storage. You’ll doubtless get less than that doing intense work in AutoCAD, but it’s a surety that you’ll get through a professional day without having to recharge. The MacBook Pro also offers up to 17 hours of battery life: the longest of any Mac ever. Note also that you can run iOS here as well, so you can open up the AutoCAD mobile app if that helps your workflow. In our review, we found that it was more than capable of running both AutoCAD and resource-hungry 3D modelling software like Maya, 3DS Max, and Fusion 360 with ease. Ensure that the device has the most recent drivers loaded as well.Running macOS Big Sur on Apple’s proprietary eight-core M1 Pro or Max chip, with up to 64GB RAM, this is the most powerful laptop Apple has ever created.To solve the problem, get in touch with the device’s manufacturers, who are the proper support source.If the crashing ceases, there is a problem with the peripheral device’s compatibility.Remove the devices (unplug them and uninstall the drivers) to see whether the crashing stops.Maya may crash while using peripheral devices like 3D mice, additional monitors, tablets, etc. How to configure Maya on Windows to use an NVIDIA GPU. ![]()
![]() ![]() Sarlat was miraculously saved by the law promulgated AugMalraux said Act. It is conceivable that in France many cities have possessed as curious and picturesque alleys, such beautiful monuments, but modernism has gradually destroyed these treasures of the past.Became sub-prefecture, she slept for almost 150 years to revitalize only in 40 years. The disappearance of the diocese (attached to that of Périgueux) during the Revolution withdrew his preeminence. The architectural quality of its monuments and its buildings demonstrates its dynamism and its ability to remain in the mainstream economy. Sarlat was again occupied by troops of Conde. The Fronde ended this favorable period in 1652.The city, while playing the same role as before, had to go twice and suffer the abuses of captain Vivans and the Vicomte de Turenne. She rallied to the king of France ten years later when the constable of Guesclin drove the English. However, it became English after the Treaty of Brétigny in 1360. and was able to rescue other cities besieged by the English Belvès, Domme Montignac. armed men of reserve of ammunition and food, the fortified town was also defended by the castles located nearby: Beynac, Castelnaud. Become episcopal city, Sarlat played a prominent role during the Hundred Years War. From the fourteenth century, bishops and consuls divided the power until the Revolution.The bishops, abbots replacing, began his architectural transformation that was completed only in the late seventeenth century. The abbey church became the cathedral of the diocese of Sarlat. In 1318, the abbey was the seat of the new diocese created by Pope John XXII. It was rebuilt in the Romanesque period between 11. She was able to remain independent and in 1153 placed under the direct protection of the Holy See in Rome.The Carolingian abbey of Sarlat is the only one to have been spared by the Vikings as situated away from the Dordogne and its tributaries. It exists in the ninth century, part of the six major monasteries of Périgord (with Paunat, Belvès Saint-Front de Perigueux, Brantome and Terrasson). The origin of the abbey is lost in legends. Monastic lordship, it reached its peak in the thirteenth century. ![]() Located in the Black Périgord, Sarlat is a medieval town that developed around a large Benedictine abbey of Carolingian origin.It is one of most beautiful detours of France. She is reputed to have the highest density of historic monuments or listed in the world. Classified town of Art and History, Sarlat-la-Canéda is a French commune in the department of Dordogne and Aquitaine region. ![]() ![]() ![]() Chinese officials reacted to the US withdrawal from the Anti-Ballistic Missile (ABM) Treaty in 2002 by saying that they would compensate as necessary. The US Sentinel (and particularly the Safeguard) missile defense systems in the 1960s and 1970s were partly intended to defend against Chinese ICBMs. Overcoming potential effects of missile defenses: Chinese planners are likely concerned that increasingly capable missile defenses could undermine China’s retaliatory capability. This action-reaction dynamic is most likely a factor in China’s current modernization. By increasing the number of silos, more ICBMs could potentially survive a surprise attack and be able to launch their missiles in retaliation. Road-mobile launchers are less vulnerable, but they’re not invulnerable. According to the US Central Intelligence Agency, China’s decision to develop the modern road-mobile ICBMs we see today was a reaction to the US Navy’s deployment of Ohio-class Trident ballistic missile submarines in the Pacific. The previous small number of fixed silos have long been seen as particularly vulnerable. Reducing the vulnerability of China’s ICBMs to a first strike: China is concerned that its nuclear deterrent is too vulnerable to a US (or Russian) surprise attack. In all these cases, it is important to remember that Chinese planning is not solely occupied with the United States, but also what Russia and increasingly India are doing: The decision to do so has probably not been caused by a single issue but by a combination of factors. However, building nearly 300 silos is certainly new. It is estimated that China currently has about 20 silos for the old (but modified) liquid-fuel DF-5 ICBM. ![]() Why is China building so many silos? Missile silos are nothing new for China, which has deployed intercontinental ballistic missiles (ICBMs) in silos since the early 1980s. ![]() In addition to these four projects, open-source researchers noted in 2020 that China might also be building a small number of silos near its traditional missile silo area near Checunzhen (Sundian) in the Henan Province.Īll told, these discoveries indicate that China might be constructing nearly 300 new missile silos. Each missile silo field appears to include a number of other facilities that might be launch-control centers, bases, and support facilities.Ĭonstruction of the Yumen, Hami, and Ordos missile silo fields follow shortly after construction began of half a dozen silos that we discovered at the PLARF training site near Jilantai in Inner Mongolia, initially described in September 2019 and reported expanding further in February 2021. The Ordos field, which began construction in April or May 2021, has a different layout and so far only appears to include about 40 silos (it could potentially grow later). Construction of the Hami field began in February 2021 and might eventually include 110 silos. The Yumen field began construction in March 2020 and appears to include 120 silos. The three sites are in different stages of construction. The third field near Ordos (Hanggin Banner) was disclosed by a military research unit at Air University in mid-August. The second field near Hami was disclosed by the Federation of American Scientists in late-July. The first missile silo field near Yumen was disclosed by the Middlebury Institute in late-June. (Some have even suggested they are not silos, but windmills.) But the satellite imagery that we have analyzed, combined with US government officials issuing apparent confirmations ( here, here, and here), indicate that the construction involves hundreds of missile silos. How many silos are under construction? The Chinese government has made no official public announcement about what it is building, and the nature, scale, and role of the suspected missile silos remains uncertain. The development requires all sides to think hard about what it means for Chinese nuclear policy, how it plans to operate its nuclear forces, how other nuclear-armed states will or should respond, and what the international nuclear nonproliferation and arms control community can and should do to reduce nuclear risks. Most will probably use the disclosure to reaffirm existing beliefs. ![]() |